a Record control number 000245699500023

a ISSN 0378-8741

a Original cataloging agency NEU GrandLibrary

a Language code of text/sound track or separate title eng

a Classification number QK9

b Item number .A58 2007

a Personal name Tunalier, Zeynep.

h Medium Electronic Document

a Title Antioxidant, anti-inflammatory, anti-nociceptive activities and composition of Lythrum salicaria L. extracts

c Statement of responsibility, etc Zeynep Tunalier, Muberra Kosar, Esra Kupeli, Ihsan Calis, K. Husnu Can Baser.

c Date of publication, distribution, etc 2007.

b Name of publisher, distributor, etc Elsevier,

a Summary, etc Lythrum salicaria (purple loosestrife) known as "Tibbi hevhulma" in Turkish is used for its several beneficial health effects against as diarrhea, chronic intestinal catarrh, hemorrhoid and eczema in the form of a decoction or a fluid extract and to treat varicose veins, bleeding of the gums, hemorrhoid and eczema, externally. Dried herbal parts of Lythrum salicaria L. (Lythraceae) were sequentially extracted with different solvents such as petroleum ether, ethyl acetate, methanol and 50% aqueous methanol. Water extract of Lythrum salicaria was also prepared under reflux. Antioxidant, anti-inflammatory and anti-nociceptive activities of all the extracts were investigated using in vitro and in vivo methods, respectively. Free radical scavenging activity (1,1-diphenyl-2-picrylhydrazyl, DPPH center dot assay), iron(III) reductive activity, capacity of the inhibition of linoleic acid peroxidation and MDA formation, anti-nociceptive activity (p-benzoquinone-induced abdominal constriction test) and anti-inflammatory activity (carrageenan-induced hind paw edema model) were used for all the extracts. In addition, the content of total phenolics, flavonoids and flavonols in all the extracts were determined with spectrophotometric methods. Results were compared with reference antioxidants via ascorbic acid, butylated hydroxytoluene, and gallic acid. Qualitative and quantitative compositions of all the extracts were analysed using a HPLC-PDA system. Polar fractions were found to be rich in flavonoids such as isovitexin and isoorientin. (c) 2006 Elsevier Ireland Ltd. All rights reserved.

a Topical term or geographic name as entry element Plant Sciences

a Topical term or geographic name as entry element Near East University Article

a Topical term or geographic name as entry element Yakın Doğu Üniversitesi Makale

a Topical term or geographic name as entry element Chemistry

a Topical term or geographic name as entry element Lythrum salicaria

a Topical term or geographic name as entry element HPLC

g Relationship information APR 4 2007, Vol 110 Issue 3, p539-547

t Title Journal of ethnopharmacology

x International Standard Serial Number 03788741

u Uniform Resource Identifier http://library.neu.edu.tr:2048/login?url=http://dx.doi.org/10.1016/j.jep.2006.10.024